3 July 2026

LATAM Airlines Launches Inaugural Cape Town–São Paulo Flight, Unlocking South America’s Largest Network

LATAM Airlines has launched its inaugural Cape Town–São Paulo service, creating a direct air link between South Africa’s Western Cape and South America. The new three-times-weekly route connects Cape Town International Airport with São Paulo Guarulhos, giving passengers onward access to more than 160 destinations across South America through LATAM’s regional network.
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LATAM Airlines Launches Cape Town–São Paulo Flights. Photo Credit © African Pilot // Kent Gibbon
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LATAM Airlines officially celebrates its inaugural flight from Cape Town on 2 July 2026, bridging the South African city directly with South America.

This milestone marks a significant expansion of LATAM Airlines transatlantic network, connecting Cape Town to the São Paulo Hub (GRU). Once in São Paulo, passengers gain immediate access to an extensive, market-leading network of more than 160 destinations throughout South America, offering unmatched regional connectivity and a superior competitive asset in the market.

CONTINENTAL AEROSPACE TECHNOLOGIES™
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Photo Credit © African Pilot // Kent Gibbon

The new Cape Town (CPT) – São Paulo (GRU) route

The newly launched direct route operates 3 times a week, providing a premium travel experience on modern wide-body aircraft.

FlightRouteDays of OperationDepartureArrivalAircraft
LA8061Cape Town (CPT) – São Paulo (GRU)Monday, Thursday, Saturday15:5019:50Boeing 787-900
LA8060São Paulo (GRU) – Cape Town (CPT)Sunday, Wednesday, Friday22:4510:55 +1Boeing 787-900

 

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Photo Credit © African Pilot // Kent Gibbon

Multi-destination advantages: Johannesburg frequency increase

To further facilitate travel and offer multi-destination flexibility across South Africa, LATAM Airlines is also expanding its established Johannesburg (JNB) to São Paulo (GRU) route.

Starting this December, the service increases from 3 to 4 weekly frequencies. This allows travellers the unique advantage of combining flights, such as arriving via Cape Town and returning via Johannesburg, ensuring convenient, open-jaw travel planning to and from the region.

FlightRouteDays of OperationDepartureArrivalAircraft
LA8059Johannesburg (JNB) → São Paulo (GRU)Tuesday, Friday, Sunday15:2020:05Boeing 787-900
LA8058São Paulo (GRU) → Johannesburg (JNB)Monday, Thursday, Saturday

(+ Tuesday starting December)

22:5012:25 +1Boeing 787-900
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Photo Credit © African Pilot // Kent Gibbon
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Photo Credit © African Pilot // Kent Gibbon

São Paulo (GRU): The ultimate hub

Our connection center at São Paulo, Guarulhos drives the region’s connectivity. By choosing LATAM Airlines, passengers access a streamlined network under a single airline code:

  • Brazil within reach: Convenient connections to more than 50 domestic destinations, including key hubs such as Río de Janeiro, Brasília, Curitiba, and Porto Alegre.
  • Regional leadership: Direct access to South America’s primary capitals: Santiago, Lima, Buenos Aires, Montevideo, and Asunción.
  • Total connectivity: A market-leading network reaching more than 160 destinations across the entire region.

Editor’s note: A quick Google search on what “open-jaw” means: “An open-jaw ticket is a travel hack where you fly into one city and depart from a different one, leaving a gap you cover by land or secondary flight.”

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